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KMID : 0371619980140020251
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Journal of Wonkwang Medical Science
1998 Volume.14 No. 2 p.251 ~ p.256
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Clinical Significance of transcranial Doppler Study in the Patients with Ruptured Cerebral Aneurysm
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Kang Sung-Don
Moon Seong-Keun
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Abstract
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The velocity of blood flow through the middle cerebral artery was measured by transcranial doppler(TCD) in 51 patients with ruptured cerebral aneurysm. A correlation between measured maximal mean blood flow velocities and clinical factors including age, Hunt-Hess grade, Fisher grade, outcome was made. Furthermore, the author analyzed the relationship of TCD velocities with delayed ischemic neurologic deficit(DIND) to determine its reliability in given patients.
An age-dependent reduction of the measured maximal mean velocities was found (r = -0.3683, p < 0.01). There was no significant difference between the flow velocities and evaluated clinical factors. When the flow velocities of 11 patients who developed DIND were compared with those of patients without deficits, no significant difference was seen. A significant increase in flow velocities in the day before the onset of DIND was found only in 3 of 11 cases. However, the rate of rise of flow velocities when studied daily, with a rate of > 50 ㎝/sec/day showed significant association with DIND(p<0.005, Fisher’s exact test). These results suggest that high TCD flow velocities do not necessarily mean poor neurological status or dense subarachnoid hemorrhage, and a early steep rise of velocities during a day can predict the development of DIND.
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KEYWORD
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Flow velocity, Transcranial Doppler, Cerebral aneurysm, Delayed ishchemic neurologic deficit
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